Long-Term Corticosteroid Therapy of Idiopathic Aplastic Anemia

Long-term corticosteroid therapy of idiopathic aplastic anemia.

The results of a long-term corticosteroid therapy performed in 55 patients with idiopathic aplastic anemia are reported. Of these patients, cure was attained in 20 patients, remission in 5, and improvement in 10. The duration of the treatment of cured cases ranged from 138 to 1109 days with a median of 522 days. The results were much better than those with other treatments conventionally perfor...

Aplastic Anemia - Diagnos tics and Therapy of Acquired Aplastic Anemia

Long-term outcome after marrow transplantation for severe aplastic anemia.

We reviewed the records and reevaluated 212 patients with aplastic anemia transplanted at the Fred Hutchinson Cancer Research Center (FHCRC) between 1970 and 1993 who survived >/=2 years and who have been followed for up to 26 years. Parameters analyzed included hematopoietic function, chronic graft-versus-host disease (GVHD), skin disease, cataracts, lung disease, skeletal problems, posttransp...

Osteoporosis and long-term corticosteroid therapy.

Sequential measurements of total body calcium by in-vivo neutron activation analysis were made in five patients treated with corticosteroid drugs for severe inflammatory disease. No evidence of osteoporosis was seen to develop during the course of 20-33 months of study. In one case a substantial rise in total body calcium was found.

Oxymetholone therapy in aplastic anemia.